Michele Kelemen

On a day that sanctions were lifted on Iran, for its compliance with last July's international nuclear agreement, Iran also released five American prisoners. The U.S. released seven Iranians, as well.

Secretary of State John Kerry addressed relations with Iran on Wednesday after the release of 10 U.S. sailors who were held for several hours when they drifted into Iranian waters.

The sister of one former U.S. Marine, who is languishing in an Iranian jail, will be in the audience at the State of the Union Tuesday. She tells NPR what she is hoping to hear from President Obama.

North Korea claims to have conducted a hydrogen bomb test. Diplomats are working on more sanctions in order to pressure North Korea to change course.

The State Department says the U.S. is not going to be the "referee" in the dispute between Saudi Arabia and Iran, but their dispute threatens U.S. goals in the region.

When the U.S. and Cuba reopened their embassies this year, American businesses started to look for opportunities on the island. They are quickly learning, though, that it will be a tough slog.

John Kavulich, president of the U.S.-Cuba Trade and Economic Council, took a deep dive into the ...

The country has been dismantling parts of its nuclear program more quickly than many expected. When international inspectors confirm Iran has met its obligations, many sanctions will be lifted.

John Kerry is on the path to log more miles than any secretary of State in history. Kerry's reason for all that travel is his firm belief in face-to-face diplomacy.

Secretary of State John Kerry tries to keep up the momentum in talks to resolve the civil war in Syria. Nearly 20 countries are meeting in New York to plan for peace talks expected next month.

Nearly two years ago, there were allegations from young children at a camp where they were supposed to be protected from war. They said French peacekeepers offered them food in exchange for sex acts.

The U.N. Security Council meets for the first time on the subject of how to clamp down on the various ways ISIS raises money — from oil sales to extortion.

It has been a year since President Obama and Raul Castro set relations on a new course. The U.S. and Cuba now have reopened embassies, but they're still testing each other on key disputes.

The U.S. and Cuba begin talks on one of the thorniest issues between them: financial claims dating back to the Cuban revolution.

Activist Aram al-Doumani has opposed the Syrian government since the uprising began in 2011. Despite talks aimed at a cease-fire this month, he's skeptical that there will be a breakthrough.

Secretary of State Kerry tried his hand at Middle East peace, and he's also trying to resolve the conflict in Syria. He's traveling to Cyprus, hoping to solve the decades old confrontation there.

American military personnel helped rescue some Americans and others in Mali after the hotel where they were staying was overrun by gunmen.

At the Group of 20 summit, President Obama reassured Turkish President Recep Tayyip Erdogan that the U.S. will do more to find a solution to Syria's political crisis, while also countering ISIS.