Scott Horsley

Known for its vast selection and knowledgeable sales staff, it's a Denver institution. Now, after 40 years, the store's longtime owner is making preparations to pass the reins to a new generation.

Focusing on long-acting contraception, such as IUDs and hormonal implants, proved to be a big success in reducing unplanned pregnancies and abortions. But political backing has been hard to come by.

It's the day after the first Republican presidential debate. Where do the candidates go from here? Who can build on momentum from the night? Who needs to recover from missteps?

In the prime-time Republican presidential debate Thursday, the candidates bragged about their records as governors and in the private sector, but the facts didn't always add up.

Even before he officially unveiled it, President Obama's plan to cut the carbon pollution produced by power plants faced significant opposition.

Fox News will use an average of national polls to decide which GOP presidential candidates take part in Thursday's prime-time debate. Pollsters say more and more people don't want to talk to them.

This post was updated at 6:45 p.m. ET

Democratic presidential hopeful Hillary Clinton released eight years worth of tax returns Friday, showing that she and her husband Bill Clinton earned $139 million since 2007. They paid nearly $44 million in federal taxes during that period. The couple's effective ...

President Obama toured a federal prison in Oklahoma on Thursday and said the nation needs to reconsider policies that contribute to a huge spike in the number of people behind bars.

In an unprecedented visit by a sitting president, Obama met with half a dozen inmates at the El Reno ...

President Obama made his case for the Iran nuclear deal at a press conference Wednesday. He said the agreement achieves its primary goal, which is to prevent Iran from developing a nuclear weapon.

The nuclear agreement with Iran could be a good example of the Obama doctrine — showing the president's determination to reach out to adversaries — that he's talked about since his first campaign for the White House.

Wisconsin Gov. Scott Walker enters an already crowd field of Republicans vying to become their party's presidential nominee. What is the case he's making to voters?

President Obama traveled to Wisconsin Friday to tout the administration's new proposed rule that could make 5 million more people eligible for overtime pay.

President Obama sought to downplay any major impact the Greek debt crisis could have on the U.S. economy. He spoke at a news conference with the president of Brazil and also addressed...

The plan raises the cap under which most workers must get overtime for working more than 40 hours a week. It doesn't require congressional approval, but is expected to be criticized by businesses.

President Obama is expected to release this week a long-awaited rule governing overtime that could affect 5 million people as soon as next year, a source familiar with the plans confirmed to NPR.

The proposed rule would more than double the salary cap under which most workers would qualify for ...

In 5-to-4 decision, the court upheld the nationwide right to same-sex marriage. Justice Anthony Kennedy authored the majority opinion. David Greene speaks with NPR's Mara Liasson and Scott Horsley.

President Obama's signature health care law survived another challenge in the Supreme Court Thursday. NPR reports on the practical and political consequences, as Obama's agenda twists its way forward.

U.S. Supreme Court ruled 6-3 to uphold the nationwide availability of tax subsidies that are crucial to the implementation of the Affordable Care Act.