The RFK Bridge is now closed.
The subway is closed. The East River bridges are closed. The Holland, the Battery, the George Washington -- all closed.
For the first time since the September 11 attacks, it's virtually impossible to get to or from Manhattan, other than for emergency vehicles.
The Lincoln and Queens Midtown Tunnels are still open. So far. (UPDATE: the Queens Midtown Tunnel is closed.)
The Governors (both of them), Mayor Bloomberg, and virtually everyone else is counseling everyone to STAY inside. Though, of course, people are not heeding that advice.