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May 12, 2008 | 48°F Overcast

Radiolab

Look How Happy These Old People are! (Balaam/flickr)

Fountains of Youth

Dr. Cynthia Kenyon looks at the genes of tiny worms, and discovers that aging may be a battle between good and evil. A literal struggle between two genes (who she calls): The Grim Reaper gene vs. The Fountain of Youth gene. And by fixing the match, she and her team at UCSF have found they can take the worms, and more than DOUBLE their lifespan. She wonders if her research may be applicable to humans. And what would a society look like if we could all live twice as long? Well, Japan may be the canary in the coal mine, because it has the fastest aging population in the whole world. Reporter Jocelyn Ford takes us there, on a tour through street fairs, nursing homes, and robot factories, to see how a society supports an aging population.

"Elixir" is real
Paro the Robot
Slideshow: Paro and Granny


Listener Comments Comment | Refresh | Back to Episode
[1]
Posted by: Andrew
September 25, 2007 - 09:21AM
W-field, NJ

Are there any references for the tradition of 'Obaa-siteh' that was introduced in this segment? I can't find it anywhere.

[2]
Posted by: Robert
October 30, 2007 - 06:57PM

I'm writing a paper on the -alteration of genes for less aging and longer life- for a class. Any additional information or sites where I can find additional information?

Thanks-

[3]
Posted by: John
December 06, 2007 - 01:02PM

I was intrigued by the Mortality podcast, but I was also disappointed that you did not take it as far as you could have. Unlike other RadioLab broadcasts, I was left with many unasked (and unanswered) questions.

For example, if the worms can have their life extended and be youthful and energetic, then things become an issue of morbidity not mortality? Part of the problem of old age as clearly demonstrate in the broadcast is inability to care for oneself, but the worm experiment seems to suggest that one can remain vigorous till the end. What would it mean to have an aged, yet functional society? Why would you need to get rid of the aged if they can still care for themselves?

Also, what evolutionary benefit is there to aging? Why would there be that gene that suppresses the youthful genes? Also, what is the relationship with reproduction and youth? Do people who don't reproduce stay more youthful? How about pets who are spayed before sexual maturity? What is the relationship between reproduction and aging? (The worm segment talked about greater youthfulness related to inability to reproduce?)

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